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Biography
Mark D. Adams, Ph.D., is a Professor in the Department of Genetics, Case Western Reserve University School of Medicine. He received a B.A. in Chemistry from Warren Wilson College in Swannanoa, NC in 1984. He received his Ph.D. in Biological Chemistry from the University of Michigan in 1990. His dissertation work involved characterization of the genes involved in branched-chain amino acid transport in Escherichia coli. As a postdoctoral fellow in the laboratory of Dr. J. Craig Venter at the National Institute of Neurological Disorders and Stroke at the NIH, Dr. Adams developed the expressed sequence tag (EST) methodology for rapid characterization of the expressed set of genes in a tissue.

As one of the founding scientists at The Institute for Genomic Research, Dr. Adams established and managed the large-scale DNA sequencing facility. The initial work focused on developing a large collection of ESTs from several hundred cDNA libraries. He also contributed extensively to determining the first genome sequence of a free-living organism, Haemophilus influenzae, as well as to several additional microbial genomes.In 1998, Dr. Adams co-founded Celera Genomics, where he was responsible for the DNA sequencing and genome annotation groups. In this role he directed the Drosophila, human, and mouse genome sequencing projects and the effort to re-sequence exons and regulatory regions of all human genes to identify novel functional SNPs.

Genetics